The extracts were cooled and filtered using whatman filter paper. A novel herbal composition containing extracts of boswellia. Pdf bael aegle marmelos extraordinary species of india. Considered a sacred tree in the hindu culture, the leaves are indispensable offerings to the lord shiva. In ayurvedic and traditional medicinal systems, different parts of a. The different varieties of bael such as mirzapuri, kagzi gonda, kagzi banarsi, kagzi etawah, narendra bael1, narendra bael2, narendra bael5, narendra bael9, pant shivani, pant sujata, etc are popular. Numerous pharmacological studies have been conducted on different parts of aegle marmelos. The alcoholic root extract of aegle marmelos showed the presence of alkaloids, carbohydrates, phenols, flavonoids, glycosides, saponins and terpens, proteins and steroids. However, despite its traditional usage as an antidiarrhoeal there is limited information regarding its mode of action in infectious forms of diarrhoea. Am belongs to the family rutaceae and is known as vilvam in tamil, bael in hindi, bilwa or sripal in sanskrit and bael tree in english nadkarni, 1986.
Review article phytopharmacological properties of aegle. Optimization of parameters for biosynthesis of silver. In order to test the antibacterial efficacy of aegle marmelos against the bacterial isolates agar diffusion test was done and the results are tabulated as follows. Aegle marmelos, commonly known as bael and belonging to the family rutaceae is an important medicinal plant in the traditional indian system of medicine, the. Pdf aegle marmelos antidiabetic activity bakrudeen ali. Aegle marmelos linn, golden apple is family rutaceae is highly reputed ayurvedic herbal. Research article healing potential of aegle marmelos in. Biological evaluation of aegle marmelos fruit extract and.
Phytochemistry and medicinal uses of the bael fruit aegle. The importance of bael in ethnomedicine and for religious purposes is of utmost. International journal of pharmaceutical, chemical and biological sciences, 2 4. Aegle marmelos, commonly known as a bael, is one of the gifts of nature to mankind. Aegle marmelos am, commonly known as bael and belonging to the family. Medicinal properties of aegle marmelos were well explained in ayurveda, indian traditional medicine. Therefore, the current investigation aims to explore the potential of aegle marmelos fruit extract amfe and isolated aegeline against the reserpineinduced pain. African journal of food science bael aegle marmelos. The english name for bael is stone apple, as its rather large fruit is like pale yellow to golden orange when ripe. Bael aegle marmelos linn, family rutacae, is also known as bale fruit tree, is a moderate sized, slender, aromatic tree, 6. Aug 01, 2011 aegle marmelos, a plant indigenous to india has been used by the inhabitants of the indian subcontinent for over 5000 years. The present study was performed to evaluate the hyperglycemic effect of aqueous extract of a. Its nutritional and medicinal properties make this fruit one of the most.
This plant is only member of the genus aegle and belongs to the family rutaceae. Bael aegle marmelos correa belongs to family rutaceae, occupies an. According to the literature, various chemical constituents and pharmacological effects have been reported for this plant. In the process of metabolic reduction, cr vi converts to trivalent chromium. There is no study on the effect of this plant on nephrotoxicity. Assessment of the elite accessions of bael aegle marmelos.
The total alcoholic, total aqueous, whole aqueous and methanolic extracts isolated from the. The report will display the kingdom and all descendants leading down to the name you choose. Bengal and vilvam in tamil is distributed throughout india in dry. Aegle marmelos pulp and powder universiti putra malaysia. Bael is a native tree fruit species in the indian subcontinent and. Aegle marmelos commonly called indian bael is a sacred tree, native to the indian subcontinent and south asia. Vidya pratishthans school of biotechnology, vsbt, research centre affiliated to savitribai phule pune university, baramati, maharashtra, india. Journal of medicinal plants research aegle marmelos linn. It has been found that aegle marmelos correa seed oil could be a suitable source for biodiesel production to. Aegle marmelos, commonly known as bael also bengal quince, golden apple, japanese bitter orange, stone apple or wood apple, is a species of tree native to. Ethnobotany and ethnoconservation of aegle marmelos l. Bael aegle marmelos known as temple garden tree has been originated from india and is also grown in most of the countries of southeast asia. Journal of medicinal plants research aegle marmelos.
The method developed was found to be accurate, precise and simple for the. Aegle marmelos, commonly known as bael has drawn the attention of worldwide prominence owing to its upholding diversified medicinal properties 1. Aegle marmelos correa bael tree is a medicinal fruit tree, widely used for healing purposes in various systems of medicines. Aegle marmelos commonly known as bael or bel, belonging to the family rutaceae, is a moderate sized, slender and aromatic tree. The present work aims to compile marmelosin based standardization of aegle marmelos, generated through the research activity using rphplc as a tool. Phytochemical screening and cytotoxic activities of aegle marmelos linn. This composition dampens leukotriene dependent inflammatory reactions via inhibiting 5. Hence, it can be targeted as novel and safe anticancer drug against breast cancer. Introduction cyclophosphamide cpa is a drug with a wide spectrum of clinical uses. Effects of aegeline, a main alkaloid of aegle marmelos correa leaves, on the histamine release from mast cells. Bael aegle marmelos is one of traditional plant of indian origin.
Static gravimetric method was used by exposing the samples to controlled. Recently, series of phenylethyl cinnamides, which included new compounds named anhydromarmeline, aegelinosides a and b were isolated from aegle marmelos leaves which are. Sep 12, 2018 aegle marmelos fresh leaves were collected, shallowly dried and powdered. Pdf antihyperglycemic and antidyslipidemic agent from. Phytochemical evaluation of leaf extracts of aegle marmelos. Rai, padmalatha s 2012 evaluation of nootropic activity of aegle marmelos extract using different experimental models in rats. It is native to india and is used in traditional medicines. Aegle marmelos linn correa, commonly known as bael or bel, belonging to the family rutaceae, is a moderate sized. Indian bael p enter a scientific or common name at any rank. The current study focuses on analyzing phytochemical constituts of aegle marmelos and its repond against the different bacteria which is found as an plant pathogen and also agaist the clinical pathogens. Hence, we evaluated the hot aqueous extract decoction of dried unripe fruit pulp of a. The aqueous and 400 mgkg body weight administered orally for five days to the ccl 4 liver and serum intoxicated by ccl.
Coumarins and alkaloids present in various parts of bael tree including roots and fruit pulp are the primary active constituents implicated for its biological activities. The results showed that flavonoids at higher doses 25 mgml. Biological activities and volatile constituents of aegle. Dec 22, 2019 bael aegle marmelos leaves at narendrapur w img 4101.
A clear, gummy sap, resembling gum arabic, exudes from. The various parts of this plant mainly leaves and fruits are widely used in traditional medicine for the treatment of various disorders. Aegle marmelos linn correa commonly known as bael or bel belonging to the family rutaceae, is a moderate sized, slender and aromatic tree. Aegle marmelos leaves extract mediated synthesis of zinc. In vitro acetylcholinesterase inhibitory activity and the. Studies on the antidiarrhoeal activity of aegle marmelos. It is a chemotherapeutic drug, belonging to the class of oxazaphosphorins, widely used in childhood, and adult malignancies as well as immunosuppressive agents for organ. Antidiabetic activity medicinal plant aegle marmelos. It is present in india, sri lanka, thailand, and malesia as a naturalized species. Aegle marmelos alkaloid c c23h27no3 cid 1752933 structure, chemical names, physical and chemical properties, classification, patents, literature, biological. Therapeutic effect of aegle marmelos fruit extract against. The administration of fruit part of aegle marmelos to wistar rats showed a significant fall in the elevated lipid peroxidation, superoxide dismutase, glutathione and. Pdf aegle marmelos antidiabetic activity bakrudeen.
Tlc and hplc fingerprint development of aegle marmelos. Phytochemistry and pharmacological properties of aegle marmelos l. Modulatory effect of dietary inclusion of aegle marmelos fruits. They showed effective inhibitory effect against escherichia coli, pseudomonas aeruginosa, proteus mirabilis, salmonella typhi, staphylococcus aureus and came to the conclusion that methanolic extracts of aegle marmelos has great antimicrobial potential. This plant is commonly known as the bael in hindi, vilvam in tamil, and bilva in the sanskrit fruit tree. Aegle marmelos am, commonly known as bael and belonging to the family rutaceae, is a tree widely distributed. Cyclophosphamide, aegle marmelos, hepatoprotective role. Aegle marmelos commonly known as bilwa or bael is an important medicinal plant in ayurveda figure 41. Keywords aegle marmelos, ethnomedical, ethnobotany, biochemical. Antifungal activity and kinetics of inhibition by essential pelzar mj, chan ec, krig nr 1998.
The favorer healthful plant aegle marmelos is historically employed in india. Similarly, determination of nitric oxide was observed in the cell culture supernatant of human pbmc as shown in figure 2. Effect of highfrequency microwave irradiation on aegle marmelos. Static gravimetric method was used by exposing the samples to controlled atmospheres maintained by saturated salt solutions. Bael, vilwam, kuvalam, bengal quince, golden apple, stone apple and wood apple belonging to order sapindales and family rutaceae is a handsome deciduous aromatic tree growing upto 8. This plant is having great potential to cure the diseases like diabetes, hyperlipidemia, peptic. Pdf antihyperglycemic and antidyslipidemic agent from aegle.
Figure 4 xrd image of silver nanoparticles synthesized from aegle marmelos leaf. Aegle marmelos leaf extract is a one of the best ayurveda medicine for diabetes mellitus. Moisture desorption isotherm of bael aegle marmelos pulp and adsorption isotherm of pulp powder were determined at 20, 30, 40 and 50 c. Primary identification of certain phytochemical constituents. Jun, 2019 a very detailed booklet, produced in pdf format on the internet, giving information on around 100 species of trees. Aegle marmelos commonly known as bael or bel, belonging to the family rutaceae, is a moderate sized, slender. Aegeline is a relatively unexplored molecule present in aegle marmelos. Biological activities of crude oil isolated from leaves of aegle marmelos indian drugs pharma. In order to test the antibacterial efficacy of aegle marmelos against the bacterial isolates agar diffusion test was done and. Anti bacterial activity of aegle marmelos against staphylococcus aureus s. Antibacterial activity of aegle marmelos against leaf, bark. Development of rphplc method for standardization of aegle.
Correa is an important medicinal plant, commonly known as bael which is belonged to family rutaceae. African journal of food science bael aegle marmelos correa. Am tree is indigenous to dry forests on hills and plains of india, pakistan, bangladesh, sri lanka, myanmar,nepal,vietnam,laos,cambodia,and ailand. The study focused on protective mechanism of marmelosin from aegle marmelos against chromium. A number of chemical constituents and various therapeutic effects of a. Evaluation of nootropic activity of aegle marmelos extract. In sanskrit, it is called bilva or sriphal or shivadruma the tree of shiva, while in hindi, it is referred to as bel or bael or sripal kritikar and basu, 1984. Bael aegle marmelos correa being an indigenous fruit occupies an important place from medicinal point of view. Aegle marmelos is a slowgrowing, medium sized tree, up to 1215 m tall with short trunk, thick, soft, flaking bark, and spreading, sometimes spiny branches, the lower ones drooping. Therapeutic effect of aegle marmelos fruit extract against dmba. Aegeline, a natural product from the plant aegle marmelos. However, the leaf extracts of the plant aegle marmelos act against anopheles stephensi, culex quinquefasciatus and aedes aegypti larvae 6, 7. The leaves, bark, roots, fruits and seeds are used extensively in the indian traditional system of medicine the ayurveda and in various folk medicine to treat myriad ailments. This study was designed to elucidate the toxicity of the widely used plant aegle marmelos in rats.
However, a study on the indonesian aegle marmelos species is rarely reported especially the hexane, chloroform and ethyl acetate extracts from this species have not been reported as most of the researches were focused on the alcoholic and aqueous extracts. Updated for itis by the flora of north america expertise network, in connection with an update for usda plants 20072010 reference for. Isolation of carbazole alkaloids and coumarins from aegle. Li109f is a novel herbal composition containing the extracts of boswellia serrata gum resin and aegle marmelos fruit. Abstract hexavalent chromium cr vi is highly toxic compared to other valence states of chromium. Oct 22, 2020 group iii aegle marmelos treateddmba induced rats treated with aegle marmelos ethanolic pulp extract 200 mgkg body weight per day for 5 weeks after tumor development about 0. However, bael is an underutilized fruit species in sri lanka. A taxonomic species within the family rutaceae bael, a fruit tree of india and southeast asia. Development and validation of lcesimsms method for. The anacardium occidentale, aegle marmelos and achyranthes aspera 50, 100, 150, 200, 300 mgkgday were administered orally for 4 days of six groups of rats n6 and the animals were kept under examination for mortality as well as any other behavioral. Immunosuppressive and cytotoxic potential of flavonoids from mitragyna parvifolia, mangifera indica and aegle marmelos. The goal of this study was to investigate the modulatory effects of dietary inclusion of aegle marmelos against cisplatininduced nephrotoxicity in wistar albino rats. Rutaceae of north america update, database version 2011 acquired.
An extensive literature has also been documented for the medicinal properties of bael. Acute and subacute toxicity studies of aegle marmelos corr. Immunosuppressive and cytotoxic potential of flavonoids. Aegle marmelos is a medicinally and horticulturally important tree. Aegle marmelos fruit extract attenuates isoproterenolinduced. Rutaceae, am known as bael in hindi and grows up to meters tall and bears thorns and fragrant owers. The present study is based on the pharmacological activity of aegle marmelos, commonly known as a bael in. Bael trees are indigenous to india and are found growing in abundance in the himalayan regions, bengal, central. Correa has been widely used in indigenous systems of indian medicine due to its various medicinal properties. Aegle marmelos, sacred tree, indigenous uses, ethnobotany. Figure 3 characterization of agnps with a peak at 400 420 nm. Synthesis of silver nanoparticles by aegle marmelos braz.
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